You can set up a vacation response in your Google Apps settings that will automatically reply to anyone who emails you. While the vacation responder is enabled, Google Apps will send a response to anyone who contacts you. If that person contacts you again after four days and your vacation responder is still enabled, Gmail will send another vacation response to remind the person that you're away from your email.
Here's how to let people know you can't respond right away:
http://support.google.com/mail/bin/answer.py?hl=en&answer=25922
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